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Description
This is a critical issue, as a decrease in muscle mass leads to a reduction in basal metabolic rate [41, 42], which could hinder the long-term benefits of obesity treatment by impairing the overall metabolic profile
Therapy with dulaglutide allows many patients to reach and maintain target HbA1c without insulin and sulfonylureas, eliminating the associated hypoglycemia risk
Most cases are mild to moderate
Discussion Among different clinical trials, both GLP-1RAs and GLP-1/GIP dual agonists are showing positive effects in reducing liver fat content and reversion of MASH [12, 38]
