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However, under pathological conditions, mitochondrial dysfunction and protein aggregation (e.g., A, -synuclein) engage in a mutually reinforcing vicious cycle, distinct from a unidirectional causal relationship

The co-treatment of the cells with 3-PLG-ibu (100 g/ml) or 0.9 M ibuprofen (the estimated drug content of 3-PLG-ibu nanocarrier) did not change the toxicity of CK treatment after 24 h

They have no diagnosis, no recent bloods, and they want it today

However, it is well known that the main risk factors for HCC development and progression are chronic infections due to viral hepatitis and alcoholic and non-alcoholic fatty liver disease, along with metabolic syndrome [306]