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This is also an illustration of the fact that, in addition to the occurrence of merely metabolic control factors, such as the lack of adequate levels of cofactors or precursors for biosynthesis, transport limitations can occur during biotransformations (see previous section)

Abdominal pain is seen in 80% of patients and does not rule out the diagnosis of CVS.27 Many patients claim to feel relief when their stomach is empty and sometimes they attempt to induce vomiting

MGBA-based interventions are poised to play a critical role in improving clinical outcomes and quality of life

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