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This study revealed that TSA exerts dual cardioprotective mechanisms by targeting VDAC1 to simultaneously inhibit ferroptosis and apoptosis, providing novel molecular targets and a theoretical basis for using TSA, an active component of Salvia miltiorrhiza, in treating ischemic heart disease (96)

The Eph proteins are divided in two subgroups, EphA and EphB based on their sequence homologies and the ability to bind their ligands, the ephrins

Within this inflammatory milieu, HSCs transition into myofibroblasts, prompting excessive extracellular matrix (ECM) production, and angiogenic factor release (Hernandez-Gea and Friedman, 2011

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