L-Carnitine Injection
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2012 doi: 10.1056/NEJMoa1211721
The therapeutic strategy integrates pharmacological and nonpharmacological modalities to target both peripheral drivers and central processing of pain
Funding This work was supported by the Agence de lInnovation de Dfense (French Defence Ministry) and the NRBC program of CEA
Penetration of stroma-rich 3D PDAC spheroids The desmoplastic ECM acts as a pathological barrier which impedes drug diffusion and penetration into PDAC tissue
