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The delivery of endocytosed cargo to lysosomes
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doi: 10.1016/j.jalz.2018.08.005 67 VogtN

However, it has also been reported that the PPP flux decrease may be an early event in the pathogenesis of sporadic PD, because in the later stages of PD, PPP flux is up-regulated in an attempt to counteract persistent oxidative stress [117]
