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In rats, intravenous immunoglobulins are effective as a therapeutic option, reducing macrophage infiltration and the severity of bortezomib-induced CIPN [103]

doi: 10.1155/2012/256024 159 ElfferichMDNelemansPJPondsRWDe VriesJWijnenPADrentM
The dosage may vary depending on the severity of the deficiency, age, and overall health status of the patient

This genotype-phenotype association is an important consideration in guiding initial vitamin B6 therapy and in predicting disease prognosis (25)