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The follow-up 2023 systematic review by the same team covered 33 studies and 1,180 participants across 23 different growth factor preparations and concluded that topical growth factor application is effective for facial skin rejuvenation, particularly when delivery is enhanced [6]

Panel 5 (Multi-System Medical Uses): outlines common therapeutic applications, including treatment of symptomatic bradycardia, reduction of gastrointestinal spasms, and use as an ophthalmic mydriatic agent