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Etheresia Pretorius, orcid.org/0000-0002-9108-2384 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Serum levels of these markers recovered after treatment to normal levels, although less completely in Crohn's disease (114) but also the transcellular uptake of luminal bacteria and bacterial components (123)

Initial treatment for patients with neurological involvement follows British National Formulary (BNF) guidance: Hydroxocobalamin 1 mg intramuscularly on alternate days for approximately 2-3 weeks (or until no further improvement) Maintenance therapy then consists of hydroxocobalamin 1 mg intramuscularly every two months Hydroxocobalamin is preferred over cyanocobalamin in the UK due to superior retention and fewer injections required

doi: 10.1515/bchm3.1992.373.2.1227