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*Correspondence: Jiang-Hua Li, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

6,7 DEX is rapidly distributed and is mainly hepatically metabolised into inactive metabolites by glucuronidation and hydroxylation

Ligand docking in the active site of ABHD11 Both the (xx(lipoly)lysine).cif and ABHD11.cif coordinates were submitted to the HADDOCK2.4 server 50 , where molecular docking for this experiment was performed based on 3D structures and ligand input

The epigenome is, indeed, influenced by metabolic factors (intracellular flux or availability of metabolites, drugs, eating habits and metabolic fitness) and environmental parameters in the strict sense (presence of pollutants, social relationships, mental and relational stress) 10
