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Drug Targets 28 JaenischR.BirdA

Monitor for excessive redness, swelling, or signs of infection at injection site

Mitochondrial respiratory complex I dysfunction promotes tumorigenesis through ROS alteration and AKT activation

Along the same line, after addition of high-dose Vit-C (1.5 M) with anti-PD1 (200 g) antibodies in a lymphoma mouse model, high-dose Vit-C therapy improved tumor immune recognition, and resulted in enhanced macrophage and cytotoxic T cell infiltration, which is not seen with anti-PD1 treatment alone
