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B12 is also involved in cellular metabolic processes such as DNA synthesis and regulation, synthesis of fatty acids and energy production

10.1208/s12249-023-02716-3 95 LimaS

Furthermore, DAG generated by PNPLA2 preferentially produces 1,3- DAG which cannot activate PKC (196), suggesting that the de novo generation of DAGs leads to insulin resistance

[Google Scholar] 35.Wilson JM, Bayer RJ, Hupe DJ
