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Translational formulation of nanoparticle therapeutics from laboratory discovery to clinical scale

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The BV and bilirubin (BR), produced by HO-1 as reducing agents, function as potent antioxidants and anti-inflammatory mediators, displaying cytoprotective properties against harmful stimuli in both in vivo and in vitro contexts

the stability was measured using the HPLC method: column Kromasil 100, 5 , 150x4.6 mm, mobile phase 0.1% triflouroacetic acid in water/acetonitrile (from 0 to 50 vol.%), gradient elution in 25 minutes, flow 1 ml/min, detection: UV at 214 nm