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Because physical exercise increases the demand on the weakened heart, measures of exercise tolerance are frequently used to monitor the severity of heart failure

Our team has guided hundreds of research labs through this exact process

Ishii the lead author, was responsible for collecting histamine release test data and making critical revisions to the manuscript

Each animal was examined every 12 days (25) or 23 days (15 C, 20) by nose- and tail-prodding with a platinum wire pick
