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Phylum porifera encode PRXs sensitive to hyperoxidation, but lack SRX For each of the 19 metazoan species, including phylum Porifera, we identified at least one AhpC-PRX1 sequence encoding the full motifs (GGLG and YF) that confer sensitivity to hyperoxidation (SO 2 H) under high concentrations of H 2 O 2 (Fig