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133 WangC.XuanX.YaoW.HuangG.JinJ
This "step therapy" approach, common in pharmaceutical benefit management, could make orforglipron the default first-line GLP-1 therapy for many patients, with injectable options reserved for orforglipron non-responders or patients with specific clinical needs for higher efficacy

USA 111 , 39553960 (2014)

PLoS One 8, e54374