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Relapse From Deep Remission After Therapeutic De-escalation in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis

The cytochrome c oxidase copper chaperone 17 (COX17), a copper metallochaperone, primarily responsible for transferring copper to synthesis of cytochrome oxidase 1/2 (SCO1/2) and cytochrome c oxidase copper chaperone 11 (COX11)

Through structure-based virtual screening and optimization, the current compounds include DDO-2728, 2-((1-hydroxy-2-oxo-2-phenylethyl)thio)acetic acid, and 4-((furan-2-ylmethyl)amino)tetrahydropyridazine-3,6-dione

In accordance with another embodiment, a method for increasing circulating and/or intracellular levels of glutathione comprises orally administering to an individual in need thereof a delayed-release, gastro-resistant capsule which contains an amount of S-acetyl-glutathione (SAG) effective to increasing circulating and/or intracellular levels of glutathione