glp-1 antagonists receptor agonists show promise in treating substance use disorders America's Poison Centers - GLP-1
Description
A post-hoc analysis of STEP 1, 2, 3, and 5 found a small but statistically significant reduction in depressive symptoms with semaglutide compared to placebo
In certain cases, specific medications may be considered
24 These effects result from several interrelated mechanisms, including improvements in insulin sensitivity, reductions in sympathetic activity, decreased plasma volume, and favorable changes in vascular function, many of which overlap with the direct pathways described above
doi: 10.1016/j.cmet.2021.01.015 [DOI] [PMC free article] [PubMed] [Google Scholar] 139
