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Li Y, Sha Z, Peng H
Safety and pharmacokinetics of single and multiple ascending doses of the novel oral human GLP-1 analogue, oral semaglutide, in healthy subjects and subjects with type 2 diabetes
Liraglutide (Victoza for diabetes, Saxenda for weight management) is administered as a daily subcutaneous injection
QMP substitutions compensate for decreased FcRn binding caused by L585 cleavage The three amino acid substitutions introduced in DIII of human albumin, QMP, greatly improve its pH-dependent binding to human FcRn (Fig
