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Available at: (Accessed November 16, 2023)

Recent studies have identified key transcription factors like MYB and WRKY involved in regulating SM biosynthesis, and Meta-QTL analysis has pinpointed crucial loci associated with increased SM production in salt-stressed environments

Activation of those genes, in turn, has been shown to extend the lifespan in a wide variety of organisms and to reduce the incidence of age-related diseases, such as diabetes, cancer, immune deficiencies, and cardiovascular disorders (Bordone and Guarente 2005)

Protocols vary, but some practitioners recommend injections every 2-3 days instead of daily, adjusting the dose accordingly