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If GLP-1s slow absorption, they could be weakening that rapid feedback loop, not by dulling desire directly, but by changing the tempo of intoxication itself
334-OR: Pemvidutide (ALT-801), a Balanced (1:1) GLP-1/Glucagon dual receptor agonist, induces rapid and marked weight loss without the need for dose titration in people with overweight/obesity
Enteroendocrine L-cells secrete GLP-1 in response to various nutrients after food intake, releasing it into the bloodstream

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