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Using in vivo TPM imaging and EM, it has been shown that fractions of small transient spines are also able to form temporary synapse components and to participate in functional circuits before being eliminated (Cane et al., Whether spine formation reflects some intrinsic properties of postsynaptic dendrites that precede synaptogenesis or if it is induced by extrinsic factors associated with presynaptic axonal terminals during synaptogenesis is still under debate

Gut-first Parkinsons disease is encoded by gut dysbiome

40,41 However, this could reflect ADR reporting biases for newer antidepressants

We fused PIF4 IDR with an N-terminal mGFPmut2 and tested its phase separation ability in vitro