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An important feature of GLP-1 RA use in type 2 diabetes is weight loss, which reduces insulin resistance and typically reaches a plateau after around 6 months of treatment
2 Metabolic dysfunction-associated fatty liver disease and MASLD remain controversial but are not considered superior to each other

However, these findings are relatively rare

13 An increase in the use of GLP1 RA as initial treatment in drugnaive patients has been observed in Denmark 14 regardless that no randomized clinical trial evidence has been published on how or whether GLP1 RA outperforms metformin in these patients