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Because retatrutide is investigational for many uses, insurance coverage might be limited
[DOI] [PMC free article] [PubMed] [Google Scholar] 1157.Mathieu C, Bode BW, Franek E, et al
In a large phase 3 obesity trial (ACHIEVE-1), orforglipron at daily doses of 3, 12 and 36 mg caused approximately: Diarrhoea: 1926% of participants (vs 9% on placebo) Nausea: 1318% (vs 2% on placebo) Constipation: 817% (vs 4% on placebo) Vomiting: 514% (vs 1% on placebo) Across multiple studies, 617% of people stopped treatment because of side effects, mostly gut-related symptoms
Liraglutide (Saxenda, Victoza) Liraglutide is a short-acting daily treatment
