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Description
Adverse events such as diarrhea, constipation, nausea, and vomiting associated with the GLP-1 RAs overlap with those seen with cancer treatments, so the patient who is undergoing treatment with an emetogenic regimen for cancer will likely experience additional weight loss, which can lead to nutritional deficiencies, loss of lean muscle mass, and loss of bone mass
Supply Chain and Distribution Advantages Beyond manufacturing, orforglipron offers significant advantages in the downstream pharmaceutical supply chain

In obese patients, I favor adjunctive treatments if they are clinically stable

Even if you tolerated maximum liraglutide without issues, the GIP component introduces a new variable
