why does semaglutide cause weight loss for Weight Change With Semaglutide
Description
Clinical trials show average weight loss can reach 15-20% of body weight - SURMOUNT-1 and STEP-1 trials confirmed this in thousands of patients
Further studies are needed to assess the potential cardiovascular and renal benefits of combination therapy and to determine suitable patient population for the therapy
GLP-RT Chemical Identity
Constitutive hGPR17L activity inhibited GLP-1 secretion, and MDL29,951 treatment further inhibited this secretion, which was attenuated by treatment with the GPR17 antagonist HAMI3379
