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The first STEP trial (a series of large clinical trials that investigated who semaglutide helps and in what context) reported a 14.9% reduction in body weight over 72 weeks for participants taking 2.4 mg weekly
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doi:10.1038/s41598-024-75965-2 Liao Y, Xie B, Zhang H, et al

HRV is a measurement of how much variety there is in the hearts rhythm
