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In fact, I have seen few patients lose more than 50 pounds with GLP-1 RAs, and most lose in the range of 20 or 30 at the most

In the pharmacovigilance investigation, we found all six GLP-1RAs (except albiglutide) were associated with hypoglycemia

I was literally on the court every day, doing nothing else

Importantly, many of these challenges are now tractable using contemporary approaches to peptide engineering, receptor biology, and translational trial design