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Liepelt I, Reimold M, Maetzler W, Godau J, Reischl G, Gaenslen A, et al
(REE x 1.55) Very Active Any activity that burns an additional 650+ calories for females or 800+ calories for males

While these processes are most marked with high-risk agents, SSRIs, typically considered low risk, have also been linked to moderate mitochondrial dysfunction and increased oxidative stress during long-term administration (37, 38)

In that trial, women taking the highest dose of tirzepatide (15 mg) lost an average of 26% of their body weight in premenopause, 23% in perimenopause, and 23% in postmenopause
