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Conclusions and future perspectives GLP-1 receptor agonists are promising therapeutic options for patients with DKD, with benefits beyond their blood glucose-lowering activity

In clinical trials, the triple agonist (GLP-1 + GIP + glucagon) produced the highest weight loss ever recorded in a drug trial

After MBS, especially after SG and RYGB, GLP-1 and peptide YY (PYY) levels increase, ghrelin levels decrease, and the peak rise (at 1530 min) in GLP-1 levels after mixed meal test or oral glucose tolerance test (OGTT) is higher than before BMS [12, 13]

versicolor rebalanced cytokine profiles in immune cells from older adults, reducing IL-5 and IL-13 while adjusting IL-1, IL-6, and interferon levelsan effect relevant to age-related immune dysfunction ( G