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Over the counter or unsupervised versions can lead to nutrient deficiencies, muscle loss, and long term rebound weight gain

Samkani et al., 2018) and increased more slowly after fat than carbohydrate intake (Elliott et al., 1993)

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The rate of weight loss on Semaglutide can vary depending on several individual factors including a patients starting weight, participation, and adherence to treatment, and lifestyle changes