brand tirzepatide 60mg/3mL (20mg/mL) Tirzepatide – 60 mg Vial
Description
With these methods, assuming no difference in cardiovascular risk between tirzepatide and comparators, it was determined that 133 participants with MACE-4 would provide 90% power to exclude the upper limit of the 95% CI of 1.8 at two-sided alpha = 0.05

Digestive effects Coffee speeds digestion while semaglutide slows it
Preprint at arXiv (2022)

On the other hand, semaglutide is a GLP-1 receptor agonist