sglt2 glp 1 Effect of combination treatment with glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter-2 inhibitors on incidence of cardiovascular and serious renal events: population based cohort study GLP-1 RA and SGLT2 Inhibitors:

Creates a steady caloric deficit Through glucose excretion, patients taking Invokana may burn up to an extra 360kcal per day. Activates nutrient-sensing longevity pathways By mimicking caloric restriction, Invokana may activate mTOR, AMPK, and SIRT1. Broad longevity benefits Modulating these longevity pathways may offer broad longevity potential, such as reduced risk of heart disease, improved kidney and liver health, better cognitive function, and moderate weight loss. What to expect 1 Day With the first dose, SGLT2 Inhibitors may help flush up to 80g of excess sugar a day, potentially reducing toxic glucose buildup and kickstarting a metabolic reset

[DOI] [PubMed] [Google Scholar] 115.Lincoff AM, Brown-Frandsen K, Colhoun HM, et al

Follow-up: What does follow-up care look like

Hydration is paramount