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Given the substantial disease burden and adverse health outcomes associated with this comorbidity, interventions aimed at reducing this risk for depression in the Type 2 diabetes population are crucial, particularly among older adults who are disproportionately affected by both conditions. Guo noted that previous research suggested that GLP-1RAs a drug also used to treat obesity and kidney disease may alleviate depression symptoms due to its ability to cross the blood-brain barrier

Max is 4.5 mg weekly

Sloop Tirzepatide (TZP) is an imbalanced agonist of the GIP and GLP-1 receptors and shows biased pharmacology at the GLP-1 receptor

With the increase in gastric transit rate and Glucagon, measures used to determine insulin dose would change, alongside increasing total daily dose of insulin