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After 48 h, hybrid 24 and semaglutide were still active while exenatide and liraglutide showed no more significant activity

Its gastroprotective and gut-healing properties could allow patients to tolerate higher GLP-1 agonist doses (and thus achieve greater weight loss) by buffering the nausea and GI distress that otherwise limit dose escalation

Davies said several agents in phase 2 and phase 3 trials have induced large reductions in both HbA1c and body weight for people with type 2 diabetes

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