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Description
The metabolic action of GLP-1GIPlanifibranor is blunted in mice with genetic or pharmacological inhibition of GLP-1R, GIPR or PPAR and is absent in DIO double incretin receptor-knockout mice, collectively suggesting that GLP-1GIPlanifibranor has substantial therapeutic value in the treatment of obesity and diabetes

For a full exploration of what GLP-1s actually do to your metabolic system beyond the scale Meto's article on the 8 metabolic effects your doctor should tell you about covers the cardiovascular, hepatic, renal, and neurological dimensions of treatment

Side effects that make eating or hydration difficult

it may create distinct side effects from semaglutide, such as erratic heart rate or specific fatigue
