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doi: 10.1111/j.1365-2125.2007.02890.x [DOI] [PMC free article] [PubMed] [Google Scholar] 54.Fineman M, Flanagan S, Taylor K, et al

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Participants taking oral semaglutide experienced clinically meaningful weight loss, with average reductions exceeding 16% when paired with diet and exercise, and substantial weight loss even without intensive lifestyle modification

And and least in those who stay on the treatment forever So what happens when you discontinue the drugs