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There is evidence that hypogonadism responds to lifestyle measures and optimization of comorbidities to some extent

Two investigators (HW and TG) independently performed the data extraction from each publication using a standardized form: publication data, baseline characteristics of the study population (sample size, sex, age, body mass index (BMI), body weight, abdominal circumference, waist-to-hip ratio, visceral adipose tissue (measured by computed tomography, magnetic resonance imaging, or dual-emission X-ray absorptiometry)), duration of follow-up, weight change during treatment and after treatment discontinuation, description of the weight management group and control group

however, when medically appropriate, obesity medications can help individuals achieve and maintain a healthier weight

The fermentation process creates bioactive peptidessmall protein fragments that act like natural ACE inhibitors, supporting cardiovascular health
