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In the 24 h meal test, encompassing three standardised meals, semaglutide reduced glucose and glucagon, and increased C-peptide levels (a marker of endogenous insulin production) in comparison with placebo

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, Safety and Efficacy of Metformin for Idiopathic Intracranial Hypertension

People experiencing significant weight gain on hormonal therapy should discuss this with their prescriber, as alternative formulations or regimens may be available
