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The in vivo half-life study in hemizygous human FcRn Tg32 mice was performed at The Jackson Laboratory (JAX Services, Bar Harbor, ME, USA), which was approved by the Animal Care and Use Committee at The Jackson Laboratory
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GLP-1 binds to GLP-1 receptor (GLP-1R), a G-coupled receptor readily found in pancreatic cells, intestine and central nervous system and moderately expressed in blood vessels, pancreatic alpha cells, peripheral nervous system, lungs, heart, kidneys and joints [7]
Hair loss was reported more frequently in patients with a greater weight loss (20%) suggesting that the events of hair loss were potentially related to the magnitude of weight loss
