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Orlistat is an oral medication that falls into a class of drugs called lipase inhibitors

Differential Effects of Metformin on Bile Salt Absorption from the Jejunum and Ileum

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Together, these results reveal that obesity-induced changes in beta-cell function may parallel or follow, rather than precede, increases in alpha-cell number, suggesting that alpha-cell proliferation may serve as a pro-active, as opposed to reactive, response to metabolic dysfunction ( Figure 4 )