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That has made researchers wonder whether GLP-1 receptor agonists might also influence mood

Data Availability Statement This is a review article and does not include any original data.

Similarly, in primary cardiac fibroblasts, GLP-1R agonism inhibited TGF- signalling activity and expression of ECM proteins, including COL1A1 and COL3A1 [25]

A previous report also demonstrated that treatment with resveratrol, a potent SIRT1 activator metabolized by gut microbiota, alters microbiota composition, decreases body weight, and improves insulin sensitivity and lipid metabolism in rodents [160,161]
