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But the trend was unmistakably toward regain once the medication was discontinued

Advances in the epidemiology, pathogenesis and management of diabetic peripheral neuropathy
Body Composition Research: Pre-clinical studies have examined Retatrutides effects on body weight, fat mass reduction, and lean mass preservation in animal models of obesity with early research suggesting the triple-agonist profile may produce more pronounced body composition changes than dual-receptor compounds in controlled experimental conditions

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