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The evaluation of patients with gastroparesis is based on symptom severity

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Tirzepatide has an additional mechanism as a dual GIP and GLP-1 agonist, meaning it activates two separate gut hormone receptors simultaneously

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Unlike semaglutide , which targets only the GLP-1 receptor, or tirzepatide , which targets GLP-1 and GIP receptors, retatrutide activates all three metabolic receptors at once

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This page explains why, who is most affected, the symptoms to recognise, and when a surgical assessment is appropriate

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