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Step 4: Apply Gentle Pressure, Not Friction After you withdraw the needle, you may see a tiny drop of blood or clear liquid

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Its primary physiological effects include: Glucose-dependent stimulation of insulin secretion Suppression of glucagon release Slowing of gastric emptying Promotion of satiety via central nervous system pathways GLP-1 receptors are expressed in multiple tissues, including: Pancreatic beta cells Gastric smooth muscle The hypothalamus Vagal afferent pathways Cardiovascular tissue Under normal physiology, endogenous GLP-1 has a very short half-life (approximately 12 minutes), as it is rapidly degraded by dipeptidyl peptidase-4 (DPP-4)