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Rectal bleeding was highest at 1 year after radiotherapy and improved thereafter
FLOW Trial: In T2DM patients with chronic kidney disease (CKD), semaglutide reduced the composite of kidney-disease progression or HF events by 27% (HR 0.73, 95% CI 0.540.98) alongside renal benefits [58]
At the time, weight loss medications were not as effective as they are today, and obesity was not yet widely treated as a chronic medical condition
