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Description
Trial registrations ClinicalTrials.gov identifiers: NCT02054897, NCT01930188, NCT01885208, NCT02128932, NCT02305381, NCT01720446, NCT02207374, NCT02254291, NCT02906930, NCT02863328, NCT02607865, NCT02863419, NCT02827708, NCT02692716, NCT02849080, NCT03021187, NCT03018028, NCT03015220.

Genetic predisposition (HLA-DR2)

Sodium butyrate reduces high-fat diet-induced non-alcoholic steatohepatitis through upregulation of hepatic GLP-1R expression
Semaglutide injections begin affecting appetite and blood sugar within hours, but meaningful weight loss typically emerges over 2-4 weeks as your body adjusts to the medication and your dose stabilizes
