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President Donald Trump has signed a sweeping executive order setting a 30-day deadline for drugmakers to lower the cost of prescription drugs in the U.S.

Large-scale pharmacoepidemiological data has not demonstrated a statistically significant increase in suicidal behaviour but there are important signals in specific subgroups, particularly those already on antidepressants or benzodiazepines

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Compared to semaglutide alone, the combination resulted in significantly greater weight loss, better body composition, and reductions in visceral fat and inflammation