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The inclusion criteria were as follows: (1) Aged 18 to 65 years

This finding suggests a mechanistic basis for the observed enzyme inhibition and points to the potential of these agents to modulate tau phosphorylation pathways critically involved in AD progression

Semaglutide and tirzepatide both follow weekly dosing schedules

Lilly redesignated the compound as LY3502970 and later assigned the international nonproprietary name orforglipron
