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A slight decline in bodyweight was observed for the first 6 days in the 100 mg/kg subcutaneous treated group (7% compared to day 0 baseline at day 6) before increasing thereafter (Supplementary Fig
Weight regain typically accelerates within the first 4 to 8 weeks after discontinuation, as appetite hormones rebound
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The cognitive battery consisted of seven standardised testing paradigms which assess different cognitive domains: crystalised intelligence (relates to knowledge and experience) [27], auditory and oral language, fluid intelligence (abilities to process and integrate) [27], processing speed, working and episodic memory, and attention and executive function
